SOMA. This upscale New American bar and eatery makes a statement on otherwise unassuming Brannan Street. Patrons feast on intriguing seafood dishes that couple French and Asian flavors, from grilled mahi mahi and smoked cod to roasted lobster. The wine menu features over 200 varieties, and a jazz trio plays evenings in the bar area. The restaurant occupies a refurbished warehouse with exposed steel beams and brick walls and is dominated by an impressive multi-story, glass-encased wine cellar.

NOB HILL. The Big 4 takes its name from four, well-known, 19th-century railroad tycoons, and the restaurant's decor is adorned with memorabilia from the era. Pan-seared Dungeness crab cakes, brioche French toast, steak and eggs, and Cobb salad are among the champagne brunch offerings that you'll find. Soups, fresh fruit, juices, and a variety of other dishes round out the tantalizing New American fare.

NORTH BEACH. Greco's European sensibility makes it a classic with city residents and travelers, who come to indulge in perfectly crafted cappuccinos, scrumptious pastries, and a casual but lively vibe. Score an outside table for the best people-watching, or pick an inside perch for quieter purposes. Bagels and focaccia sandwiches provide savory, substantial alternatives, and tiramisu is a fresh, delicious treat any time of day. Attentive, conscientious service makes the place even more appealing.

NOB HILL. Entering this Euro-Asian restaurant atop the Plaza building, you'll feel as if you've just stepped into an exciting, undersea world. The house specialty, crab prepared three ways, is incredible, and roast crab is a delicious signature dish too. Also famed are garlic noodles, whose recipe is so well-guarded that they must be prepared in a separate kitchen! Well-trained staff.

SOMA. Ask anyone about DeLessio's and their eyes will sparkle with delight as they mention the place's decadent macaroni and cheese, tasty gourmet sandwiches, and impressive buffets. When the topic of desserts and pastries comes up, however, those same eyes absolutely glaze over in awe. Folks can't praise the bakery's bounty enough, whether they go for mini-cupcakes, lemon decadence cake, flaky croissants, scones, chocolate brioche, bread pudding, or any of the other myriad temptations. Perfect for any meal or snack.